Tom Brady: There is no way Brady is not going to be out on the field despite being listed as questionable with a knee injury. Yes Brady has missed practice time but that is because he is 39 and not because he is hurting. Put him in there and don't worry.
Latavius Murray: Murray is dealing with an ankle injury but he will be in there according to multiple reports. Once again Murray has been productive but in a very understated way. He remains a firm RB 2 on workload alone.
Mark Ingram: Yes Ingram has been doing work in practice but he still is not yet cleared in terms of the NFL's concussion protocol. He is also in a strict timeshare with Sean Payton's pet Tim Hightower so Ingram would be nothing more than a RB 2 anyways.
Chris Hogan: Malcolm Mitchell owners are hoping Hogan sits out another game with his ongoing back woes as the latter was very productive in his place last week. Hogan is unlikely to play as he has done almost nothing in practice this past week and so Mitchell looks like a prime WR 3 play once again.
Rob Gronkowski: It will mark the second straight game Gronk will have missed with the chest/lung injury he suffered in Week 10. Also it adds on to the missed games Gronk began the year with as he once again reminds us how fragile he is and how much of a draft risk he remains.
Ryan Mathews: Injuries are nothing new for Ryan Mathews who has made a career out of them. This time it is an MCL injury in his knee that will likely keep Mathews out a few games. Also Darren Sproles has a rib injury of his own which means rookie Wendell Smallwood could be a huge value play this week.
Jeremy Maclin: Maclin will sit for the third straight game with a groin injury and so Tyreek Hill gets a shot to be a WR 3 in PPR formats. Also look for a big game out of tight end Travis Kelce.