Indianapolis Colts QB Andrew Luck is unlikely to be cleared in time to start against the Pittsburgh Steelers in the annual late-game Thanksgiving Day special and his loss reverberates to a wide spectrum for a number of reasons. Obviously Luck's fantasy football owners lose out big-time in such a big matchup against an awful Steelers defense. On a secondary front, Luck's loss is a big blow to all of us who were looking forward to a great on paper matchup between the Colts and Steelers. That is obviously fallen by the wayside as Tolzien is a career backup for a reason and the Steelers likely will blow the Colts out as a result. Also the Indy skill position players are going to see their numbers ebb a bit as well due to Luck's absence. Pretty much everyone loses with Luck being out both in real and in fantasy football.